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Intra-articular injection · Triple Formula

ORTHOFLEX gel

Essential elements of natural articular cartilage

A bio-matrix combining three natural cartilage components — Hyaluronic Acid, Chondroitin Sulfate, and Glucosamine — for cartilage repair, mobility improvement, and lasting pain relief.

ORTHOFLEX gel product

Product Specifications

ProductORTHOFLEX gel®
Hyaluronic Acid36 mg / 2.25 ml
Chondroitin Sulfate67.5 mg / 2.25 ml
N-Acetylglucosamine67.5 mg / 2.25 ml
Molecular Weight3.0 MilDa
Volume2.25 ml prefilled syringe
Treatment1 injection per treatment (twice a year, every 6 months)
Effect Duration6 months
ApplicationKnee joint and other synovial joints
SterilizationAutoclave
TechnologyBiofermentation
Shelf Life2 years
Storage+2°C to +25°C, do not freeze
CertificationsCE, ISO 13485, GMP — Class III Medical Device

What is ORTHOFLEX gel?

ORTHOFLEX gel is a bio-matrix in the form of a sterile, viscoelastic solution consisting of a combination of highly purified cross-linked biopolymers: hyaluronic acid, chondroitin sulfate, and n-acetylglucosamine.

It is very similar to the synovial fluid that occurs naturally in the joints, where it acts as a lubricant and shock absorber. The high molecular weight (3.0 MilDa) guarantees excellent efficiency and a strong therapeutic effect.

Triple-Action Formula

01

Hyaluronic Acid

The major component of synovial fluid — responsible for lubrication and cushioning in joints, providing mechanical support and acting as a shock absorber.

02

Chondroitin Sulfate

Delivers nutrients to joint cartilage, stimulates new cartilage growth, blocks degrading enzymes, and maintains the elasticity and plasticity of cartilage.

03

Glucosamine

Plays a vital role in building and repairing cartilage. Stimulates the manufacture of glycosaminoglycans (GAGs) — key structural components of cartilage.

They work much more effectively when used together!

Indications

  • Osteoarthritis treatment
  • Post-arthroscopy pain relief
  • Following meniscus repair
  • Following crossed ligament reconstruction
  • Auxiliary treatment for osteochondral defects
  • Pain and restricted mobility from traumatic joint pathology

Treatment Protocol

ORTHOFLEX gel must be administered strictly intra-articularly, twice a year — every 6 months, according to the doctor's recommendations. Any joint effusion present should be removed by aspiration before injection. An articular rest of approximately 24 hours post-injection is recommended. Obtained by biofermentation, its synthetic origin completely eliminates the risk of allergic reactions.

ORTHOFLEX gel triple formula detail
Bio-Matrix Formula

The Closest Formula to Natural Articular Cartilage

ORTHOFLEX gel is formulated to mirror the natural composition of healthy articular cartilage. By combining three essential building blocks — Hyaluronic Acid, Chondroitin Sulfate, and N-Acetylglucosamine — it delivers comprehensive joint support in a single injection.

The high molecular weight (3.0 MilDa) cross-linked biopolymer matrix ensures the solution stays in the joint longer, providing sustained lubrication, structural support, and active cartilage regeneration for up to 6 months per treatment cycle.

  • Mimics the natural composition of synovial fluid
  • Replenishes all three key cartilage building blocks
  • Twice-yearly treatment — minimal clinical visits
  • No risk of allergic reaction (synthetic biofermentation)
  • Effective post-arthroscopy and ligament reconstruction

Interested in ORTHOFLEX gel?

Contact our team for product information, pricing, or to request samples.

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